Peer support after hospital stay may cut overdose and infection risk

NCT ID NCT06843213

Recruiting now Disease control Sponsor: University of Pennsylvania Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a program called THRIVE, where a trained peer (someone with lived experience) meets with patients in the hospital and sends weekly texts for 12 weeks after discharge. The goal is to see if this support helps reduce non-fatal overdoses and skin infections compared to just giving a resource handout. About 390 adults with opioid use disorder will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: peer-led health resilience and promotion program
What this could lead to: If it works, this could provide a simple, low-cost way to reduce overdoses and infections in people recovering from opioid use disorder.
What could go wrong: This is an early-stage study with 390 participants, so results may not apply to everyone. The program relies on peer support and text messages, which may not work for all individuals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Harm Reduction opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HARM REDUCTION HEALTH PROMOTION OPIOID-USE DISORDER

Contacts and locations

Locations

UPMC Mercy Hospital
NOT_YET_RECRUITING

Pittsburgh, Pennsylvania, 15203, United States
UPMC Presbyterian-Montefiore Hospital
RECRUITING

Pittsburgh, Pennsylvania, 15213, United States
UPMC Shadyside Hospital
NOT_YET_RECRUITING

Pittsburgh, Pennsylvania, 15232, United States

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