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New combo therapy aims to stall liver cancer progression

NCT ID NCT05620771

Recruiting now Disease control Sponsor: Northwestern University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is for adults with advanced liver cancer (hepatocellular carcinoma) that is hard to treat. It compares two standard drug regimens — immunotherapy (atezolizumab + bevacizumab) or targeted pills (lenvatinib or cabozantinib) — given after a liver-directed radiation treatment called Therasphere (Y-90). The goal is to see which combination better delays cancer growth. About 200 participants will be enrolled.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEPATOCELLULAR CARCINOMA

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Northwestern Medicine Delnor Hospital

    RECRUITING

    Geneva, Illinois, 60134, United States

    Contact Email: •••••@•••••

  • Northwestern Medicine Grayslake Outpatient Center

    RECRUITING

    Grayslake, Illinois, 60030, United States

    Contact Email: •••••@•••••

  • Northwestern Medicine Kishwaukee Hospital

    RECRUITING

    DeKalb, Illinois, 60115, United States

    Contact Email: •••••@•••••

  • Northwestern Medicine Lake Forest Hospital

    RECRUITING

    Lake Forest, Illinois, 60045, United States

    Contact Email: •••••@•••••

  • Northwestern Medicine Orland Park

    RECRUITING

    Orland Park, Illinois, 60462, United States

    Contact Email: •••••@•••••

  • Northwestern Medicine Warrenville

    RECRUITING

    Warrenville, Illinois, 60555, United States

    Contact Email: •••••@•••••

  • Northwestern University

    RECRUITING

    Chicago, Illinois, 60611, United States

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