Liver cancer trial combines radiation beads with two different drug strategies

NCT ID NCT05620771

First seen Nov 01, 2025 · Last updated May 06, 2026 · Updated 21 times

Summary

This study is for adults with advanced liver cancer (HCC) who cannot have surgery. It compares two treatment sequences: first, tiny radioactive beads (Therasphere) are placed in the liver to deliver radiation directly to tumors. Then patients receive either immunotherapy (atezolizumab + bevacizumab) or targeted pills (lenvatinib or cabozantinib). The goal is to see which combination keeps the cancer from growing longer. About 84 people will take part.

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Contacts and locations

Locations

  • Northwestern University

    Chicago, Illinois, 60611, United States

Conditions

Explore the condition pages connected to this study.