Can a common antibiotic ease long-term lyme misery?

NCT ID NCT05219929

First seen Jan 11, 2026 · Last updated May 01, 2026 · Updated 15 times

Summary

This study looks at whether tetracycline, an antibiotic, is tolerable and can help people with Post-Treatment Lyme Disease (PTLD) — ongoing symptoms like fatigue after standard Lyme treatment. About 60 adults will receive either tetracycline or a placebo for 3 months, then switch to the other option for 3 more months. The main goal is to see if people can tolerate the drug and if it reduces fatigue.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Johns Hopkins Lyme Disease Research Center

    Lutherville, Maryland, 21093, United States

Conditions

Explore the condition pages connected to this study.