Can a common antibiotic ease lingering lyme fatigue?
NCT ID NCT05219929
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study tested whether taking tetracycline for 3 months is tolerable for people with Post-Treatment Lyme Disease (PTLD) โ those who still have symptoms like fatigue after standard antibiotic treatment. 60 adults received either tetracycline or a placebo, then switched treatments. The main goal was to see how many side effects occurred and if people could stick with the therapy. Results may help decide if larger studies on symptom relief are worthwhile.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Johns Hopkins Lyme Disease Research Center
Lutherville, Maryland, 21093, United States
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