Can a common antibiotic ease lingering lyme fatigue?

NCT ID NCT05219929

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether taking tetracycline for 3 months is tolerable for people with Post-Treatment Lyme Disease (PTLD) โ€” those who still have symptoms like fatigue after standard antibiotic treatment. 60 adults received either tetracycline or a placebo, then switched treatments. The main goal was to see how many side effects occurred and if people could stick with the therapy. Results may help decide if larger studies on symptom relief are worthwhile.

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Conditions

The condition(s) this trial relates to.

Post-Lyme Disease Syndrome post-treatment Lyme disease syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Johns Hopkins Lyme Disease Research Center

    Lutherville, Maryland, 21093, United States

More trials for these conditions

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