Post-treatment Lyme disease syndrome

This study tests a device called the Sana Pain Reliever, a mask with earbuds that delivers pulses of light and sound for 15 minutes at a time. Researchers want to see if it can reduce chronic pain and improve sleep in people with post-treatment Lyme disease syndrome. The trial in…

This study tests a small, non-invasive device that gently stimulates a nerve in the ear (taVNS) to see if it is safe and tolerable for people with persistent symptoms after Lyme disease treatment. The trial will enroll 24 adults who still have symptoms like fatigue or pain months…

This study tests a new way to treat brain fog in people with post-treatment Lyme disease. Participants will play computer-based thinking games at home while receiving either real or fake brain stimulation (tDCS) for 4 weeks. Researchers will check if the active stimulation improv…

This early-stage trial tests whether giving the antibiotic ceftriaxone every 5 days for 6 weeks can safely reduce persistent symptoms like fatigue and pain in people who have already been treated for Lyme disease. About 44 adults aged 18 to 75 will receive either the drug or a pl…

This study tests a dietary supplement called lumbrokinase in 120 adults with Long Covid, post-treatment Lyme disease syndrome, or ME/CFS. Participants take the supplement daily for 6 weeks. The goal is to see if it improves overall health and quality of life, as measured by a sim…

This study investigates whether the bacteria causing Lyme disease can survive antibiotic treatment and cause ongoing symptoms. Researchers will follow 700 participants, including those with chronic Lyme disease, recovered individuals, and healthy volunteers, using blood tests, sp…

This study explores the real-life experiences of people who had Lyme disease during or before pregnancy and are now raising children. Participants fill out surveys about their health, mental well-being, and child development, then take part in an interview to share their personal…

This study follows 40 pregnant women with Lyme disease to see how the infection might affect their baby's development. Researchers will monitor pregnancies and check infant growth, thinking, and motor skills from birth to 18 months. The goal is to learn if Lyme exposure in the wo…

This research study collects health information from 10,000 people with brain inflammation conditions like Long COVID, ME/CFS, and autoimmune diseases. Participants use a smartphone app to share symptoms, health history, and wearable data. The goal is to find disease subtypes and…