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New shot may curb heavy drinking in reward-driven people

NCT ID NCT05028062

Recruiting now Disease control Sponsor: University of Pennsylvania Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a monthly injection of naltrexone (a medication that blocks alcohol's rewarding effects) helps people who drink for pleasure reduce heavy drinking more than a placebo. About 60 adults with alcohol use disorder who drink heavily will receive either the shot or a placebo, plus four counseling sessions. The goal is to see if the medication leads to fewer heavy drinking days over 8 weeks.

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Conditions

The condition(s) this trial relates to.

alcohol abuse

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALCOHOL USE DISORDER ALCOHOLISM

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Pennsylvania Center for Studies of Addiction

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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