Can Brain-Training games rewire the mind to fight alcohol addiction?
NCT ID NCT04244032
First seen Sep 16, 2026 · Last updated Sep 17, 2026 · Updated 1 time
Summary
Researchers at the University of Florida are testing whether computerized cognitive training can help people with alcohol use disorder improve their memory, self-control, and thinking skills during inpatient treatment. Participants complete up to 12 sessions of adaptive brain-training tasks that adjust to their ability level. The trial measures changes in working memory, inhibitory control, and general executive function, and tracks whether these changes relate to drinking after discharge.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- computerized cognitive training programs targeting working memory, inhibitory control, and cognitive bias
- What this could lead to
- If it works, this could add a low-cost, non-drug tool to inpatient alcohol treatment that helps people think more clearly and stay sober after discharge.
- What could go wrong
- The trial is very small, with only 22 participants, and it is not yet clear whether brain-training gains last or translate into less drinking. Computerized training may improve test scores without changing real-world outcomes.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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22 people
The number who actually took part.
- Started
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Apr 2021
- Finished
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Sep 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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25 to 64 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Minimum of 10 years of education * Meet DSM-5 criteria for alcohol use disorder Exclusion Criteria: * Medical histories confounding interpretation regarding change in neuropsychological functioning (e.g., stroke) * Meet DSM-5 criteria for current/unremitted psychotic, panic, or bipolar disorders
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Florida
Gainesville, Florida, 32610, United States
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