Spinal taps open a window on alcohol use disorder

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: The study participant: 1. has given his/her written and oral informed consent to participate in the study 2. presents a breath alcohol concentration (BrAC) below 10mg% (10mg/dl) at the study visit Exclusion Criteria: The study participant: 1. is pregnant or breastfeeding 2. has an ongoing neurological or psychiatric disease except for Alcohol Use Disorder 3. has an ongoing or previous disease that affects either the safety of the study participant following a spinal tap or the outcome measures of the study 4. currently uses (within 30 days of enrollment) medication that affects either the safety of the study participant following a spinal tap or the outcome measures of the study 5. currently uses (within 30 days of enrollment) medications for the treatment of Alcohol Use Disorder or alcohol abstinence that affects the mesolimbic dopamine system 6. currently uses (within 30 days of enrollment) dietary supplements, including energy drinks, that may affect the safety for the study participant following a spinal tap or may have an impact on the outcome measures 8\. currently and frequently uses (within 1 year of enrollment) drugs of abuse other than alcohol and nicotine. 9\. participates in another interventional clinical trial within 30 days of enrollment 10\. has a local infection or a tattoo in the lower back region 11\. anatomical anomalies in the lower spine region, e.g. following prior spine surgery, that obstructs the procedure of a spinal tap 12\. has prior history of allergic reactions to local anaesthetics 13\. presents pathological findings during medical examination that may affect the safety for the study participant following a spinal tap or the outcome measures 14\. is considered to be unfit for study participation for other reasons than stated above