Could a common blood pressure drug help dementia with lewy bodies?
NCT ID NCT04760860
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial will test whether terazosin, a drug currently used for high blood pressure and enlarged prostate, is safe and tolerable for people with dementia with Lewy bodies. Forty participants will receive either terazosin or a placebo for 15 weeks. The study focuses on side effects and how well people stick with the treatment, not on whether it improves symptoms.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Terazosin hydrochloride (a drug usually used for high blood pressure or enlarged prostate)
What this could lead to
If it works, this could point toward a new way to ease motor symptoms in dementia with Lewy bodies.
What could go wrong
This is a very early, small trial (40 people) focused on safety and tolerability, not on proving the drug works. It may fail to show benefit or cause side effects like low blood pressure.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Iowa
Iowa City, Iowa, 52252, United States
Contact Email: •••••@•••••
Contact
Contact Email: •••••@•••••