Canadian trial tests monkeypox drug in outpatients
NCT ID NCT05534165
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This Canadian study tests whether the antiviral drug tecovirimat (TPOXX) helps non-hospitalized adults with monkeypox recover faster. About 120 participants will receive either the drug or a placebo. The main goal is to see how quickly skin lesions heal and whether running such a trial in Canada is practical.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Tecovirimat (also known as TPOXX), an antiviral drug
What this could lead to
If it works, this could provide an effective treatment for monkeypox that speeds up recovery and reduces symptoms in outpatients.
What could go wrong
This is a feasibility study with only 120 participants, so results may not be definitive. The trial is currently suspended, and tecovirimat may not work better than a placebo.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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St. Michael's Hospital
Toronto, Ontario, M5B 1W8, Canada
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St. Paul's Hospital, BC Centre for Excellence in HIV/AIDS
Vancouver, British Columbia, V6Z 1Y6, Canada
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Toronto General Hospital
Toronto, Ontario, M5G 2N2, Canada