Could a simple mist replace surgery for bleeding tonsils?

NCT ID NCT06580509

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

After a child has their tonsils removed, bleeding can sometimes occur and may require another surgery. This pilot study tests whether a nebulized mist of the drug tranexamic acid (TXA) can stop the bleeding without needing to touch the sore area. Twelve children aged 2 to 17 who experience post-tonsillectomy bleeding will receive either the TXA mist or a placebo. The main goal is to see if the treatment is feasible and to measure how much of the drug enters the body.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Tranexamic acid (TXA) given as a nebulized mist
What this could lead to
If it works, this could offer a simple, non-surgical way to stop bleeding after tonsil removal in children, reducing the need for repeat surgery or blood transfusions.
What could go wrong
This is a very early pilot study with only 12 children, so it is too small to prove effectiveness. The treatment may not work as hoped, and there is a risk of side effects from the medication.

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Conditions

The condition(s) this trial relates to.

Blood Loss, Surgical

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Hospital

    RECRUITING

    San Antonio, Texas, 78229, United States

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