Zapping the brain: can tDCS rewire schizophrenia?
NCT ID NCT05435300
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study looks at whether a gentle brain stimulation technique called tDCS can change the density of synapses (connections between brain cells) in people with schizophrenia. Researchers will use special PET scans to measure these changes in 20 participants. The goal is to understand how tDCS works in the brain, not to treat symptoms directly.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- transcranial direct current stimulation (tDCS)
- What this could lead to
- If successful, this could reveal how tDCS affects brain connections, pointing toward better treatments for schizophrenia.
- What could go wrong
- This is a very small, early study (20 people) focused on measuring brain changes, not on treating symptoms. Results may not lead to new therapies.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Centre for Addiction and Mental Health
RECRUITINGToronto, Ontario, M5T 1R8, Canada
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Other studies related to the condition(s) this trial covers.
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