Could TB treatment be cut from 6 months to 8 weeks? major trial launches

NCT ID NCT06114628

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests new drug combinations to treat pulmonary tuberculosis (TB) faster than the standard 24-week regimen. About 2500 adults with TB will receive one of several experimental combinations, including two new drugs (BTZ-043 and GSK3036656), for 8 to 16 weeks. Researchers aim to find a shorter, equally safe and effective treatment that could also work for drug-resistant TB.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Joint Clinical Research Centre

    RECRUITING

    Kampala, Uganda

  • Kibong'oto Infectious Diseases Hospital

    RECRUITING

    Moshi, Tanzania

  • Makerere University Lung Institute

    RECRUITING

    Kampala, Uganda

  • NIMR Mbeya

    RECRUITING

    Mbeya, Tanzania

  • NIMR Mwanza

    RECRUITING

    Mwanza, Tanzania

  • National Lung Hospital

    ACTIVE_NOT_RECRUITING

    Hanoi, Vietnam

  • PMSI Institute of Pneumology "Chiril Draganiuc"

    ACTIVE_NOT_RECRUITING

    Chisinau, Moldova

  • Pnth/Oucru

    ACTIVE_NOT_RECRUITING

    Ho Chi Minh City, Vietnam

  • TASK Brooklyn

    RECRUITING

    Cape Town, South Africa

  • TASK Eden

    RECRUITING

    George, South Africa

  • University of Cape Town Lung Institute

    RECRUITING

    Cape Town, South Africa

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