A simple taste test could revolutionize depression treatment
NCT ID NCT03645447
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study explores whether a taste test can serve as a diagnostic tool for depression. Participants with untreated major depressive disorder will take a taste test before and after starting an antidepressant prescribed by their doctor, and again six to eight weeks later. The goal is to see if changes in taste sensitivity correlate with improvements in mood, potentially offering a new way to predict which antidepressant will work best for each person.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
taste test device
What this could lead to
If successful, this taste test could become a quick, low-cost tool to help doctors choose the right antidepressant for each patient.
What could go wrong
This is an early-stage study with 240 participants. The taste test may not reliably predict treatment outcomes, and results may not apply to all types of depression.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Honiton Surgery
Honiton, Devon, EX14 2LY, United Kingdom
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Humber Teaching NHS Foundation Trust
Hull, Yorkshire, United Kingdom
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Jhoots Pharmacy
Bristol, Avon, BS9 3AG, United Kingdom
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West Walk Surgery, Yate
Bristol, BS37 4AX, United Kingdom