Which pill works best for Post-Surgery pain?
NCT ID NCT07587645
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tested two different painkillers given before leg surgery to see which one better prevents pain afterward. 46 adults took either tapentadol or pregabalin for three days before their operation. Researchers measured pain levels and how much extra pain medicine was needed after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- tapentadol and pregabalin
- What this could lead to
- If one drug works better, it could offer a more effective way to manage pain after leg surgery.
- What could go wrong
- This is a small pilot study with only 46 people, so results may not apply to everyone. The drugs also have side effects like nausea or dizziness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hospital Regional "General Ignacio Zaragoza," ISSSTE
Mexico City, Mexico City, 09360, Mexico
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