New immune globulin drug shows promise for rare nerve diseases in japan

NCT ID NCT05084053

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed Phase 3 study tested TAK-771, a combination of immune globulin and hyaluronidase, in 26 Japanese adults with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) or multifocal motor neuropathy (MMN). The main goals were to check for side effects and see how well the drug controls symptoms over up to 45 months. Participants received infusions every 2, 3, or 4 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

TAK-771 (immune globulin infusion with hyaluronidase)

What this could lead to

If successful, TAK-771 could offer a new treatment option to help control symptoms of CIDP and MMN in Japanese patients.

What could go wrong

This is a small, completed Phase 3 study with only 26 participants, so results may not apply broadly. As with any immune globulin treatment, there is a risk of side effects like infusion reactions or blood clots.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic inflammatory demyelinating polyradiculoneuropathy multifocal motor neuropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aichi Medical University Hospital

    Nagakute, Aichi-ken, Japan

  • Asahikawa Medical Center

    Asahikawa, Hokkaido, Japan

  • Chiba University Hospital

    Chiba, Japan

  • Chubu Rosai Hospital

    Nagoya, Aichi-ken, Japan

  • Fujita Health University Hospital

    Toyoake, Aichi-ken, Japan

  • Higashimatsuyama Municipal Hospital

    Saitama, Japan

  • Hiroshima University Hospital

    Hiroshima, Japan

  • Hyogo College of Medicine Hospital

    Nishinomiya, Hyōgo, Japan

  • Juntendo University Hospital

    Bunkyo-ku, Tokyo, Japan

  • Kansai Rosai Hospital

    Amagasaki, Hyōgo, Japan

  • Kumamoto University Hospital

    Kumamoto, Japan

  • Kyushu University Hospital

    Fukuoka, Japan

  • Nara Medical University Hospital

    Kashihara, Nara, Japan

  • National Center of Neurology and Psychiatry

    Kodaira, Tokyo, Japan

  • Shiga University of Medical Science Hospital

    Ōtsu, Shiga, Japan

  • St.Marianna University School of Medicine Hospital

    Kawasaki, Kanagawa, Japan

  • Toho University Omori Medical Center

    Ōta-ku, Tokyo, Japan

  • Tohoku Medical and Pharmaceutical University Hospital

    Sendai, Miyagi, Japan

  • Tokushima National Hospital

    Yoshinogawa, Tokushima, Japan

  • Tokushima University Hospital

    Tokushima, Japan

  • Tokyo Women's Medical University Hospital

    Shinjuku-ku, Tokyo, Japan

  • Toyama University Hospital

    Toyama, Japan

  • Yamaguchi University Hospital

    Ube, Yamaguchi, Japan