Blood test may Fine-Tune IVIg dosing for rare nerve disorders

NCT ID NCT04356781

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looked at 20 adults with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) or multifocal motor neuropathy (MMN) who were starting intravenous immunoglobulin (IVIg) treatment. Researchers measured changes in IgG levels in the blood after the first dose to see if those changes could predict the long-term dose each patient would need. The goal is to make dosing more precise, reduce side effects, and lower costs.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Intravenous immunoglobulin (IVIg)
What this could lead to
If successful, this could help doctors find the right IVIg dose for each patient more quickly, saving time and reducing side effects.
What could go wrong
This is a small, completed observational study with only 20 participants. It does not test a new treatment, so it may not lead to changes in practice.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Walton Centre NHS Foundation Trust

    Liverpool, Merseyside, L9 7LJ, United Kingdom

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