New cocktail of pills plus procedure aims to fight untreatable liver cancer

NCT ID NCT07309419

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether combining a liver-directed procedure (TACE) with an oral triple-drug cocktail works better than TACE plus standard targeted therapy and immunotherapy for people with liver cancer that cannot be surgically removed. About 222 participants will be randomly assigned to one of the two treatment groups. The main goal is to see if the new combination helps people live longer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Apatinib, Camrelizumab, Thalidomide, Capecitabine, and Compound cantharides capsule

What this could lead to

If successful, this could offer a new first-line treatment option for people with liver cancer that cannot be removed by surgery, potentially improving survival.

What could go wrong

This is an early-phase trial with only 222 participants, so results may not apply to everyone. The combination of multiple drugs may cause significant side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.