Supercharged immune cells take on viruses in transplant patients
NCT ID NCT01325636
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested whether giving patients special immune cells (T cells) that target CMV or adenovirus could control these infections after a stem cell transplant. Sixteen children and adults received one or two doses of these cells. The goal was to reduce virus levels in the blood safely. The trial was early-stage, so results are preliminary.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
specific immune cells (CD4 and CD8 T cells) targeting CMV or adenovirus
What this could lead to
If it works, this could offer a way to control dangerous viral infections after stem cell transplants without relying on drugs that have side effects.
What could go wrong
This was a small, early-phase trial with only 16 patients, so results may not apply broadly. The treatment could also cause graft-versus-host disease or other immune reactions.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Biotherapy department, Hôpital Necker - Enfants Malades
Paris, 75743, France