Massive study tracks 2500 kids from womb to uncover allergy roots

NCT ID NCT04798079

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study enrolls 2500 pregnant women and follows their children from before birth up to age 3 (or 6 for those who continue). Researchers collect biosamples and environmental data to identify early-life markers and biological pathways that lead to food allergy and atopic dermatitis (eczema). The goal is to understand why some children develop these allergic conditions, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could reveal early-life markers and biological pathways that predict food allergy and eczema, pointing toward future prevention strategies.

What could go wrong

This is an observational study, not testing a treatment. It may not identify clear risk markers, and findings may not lead to direct interventions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

allergic disease atopic eczema food allergy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Arkansas Children's Hospital

    Little Rock, Arkansas, 72202, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Henry Ford Health System, Division of Allergy and Immunology

    Detroit, Michigan, 48202, United States

  • Johns Hopkins Children's Center, Department of Allergy & Immunology

    Baltimore, Maryland, 21287, United States

  • Kravis Children's Hospital, Jaffe Food Allergy Institute, Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States

  • Massachusetts General Hospital, Translational and Clinical Research Center

    Boston, Massachusetts, 02114, United States

  • National Jewish Health

    Denver, Colorado, 80206, United States

  • North Carolina Children's Hospital: Department of Pediatrics, Division of Allergy, Immunology and Rheumatology

    Chapel Hill, North Carolina, 27599, United States

  • Northwestern University Feinberg School of Medicine: Dept of Dermatology

    Chicago, Illinois, 60611, United States

  • Sean N. Parker Center for Allergy & Asthma Research at Stanford University

    Stanford, California, 94040, United States

  • Texas Children's Hospital

    Houston, Texas, 77030, United States

  • University of Wisconsin School of Medicine and Public Health

    Madison, Wisconsin, 53792, United States

  • Vanderbilt University Medical Center Department of Pediatrics Division of Pediatric Allergy, Immunology, and Pulmonary Medicine

    Nashville, Tennessee, 37232, United States