Could a daily probiotic help tame schizophrenia?
NCT ID NCT04226898
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether a daily synbiotic supplement (a mix of probiotics and prebiotics) can reduce symptoms of schizophrenia when taken alongside standard antipsychotic medications. Researchers are enrolling 68 adults with schizophrenia or schizoaffective disorder who have ongoing symptoms. Half will get the supplement, half a placebo, and changes in symptoms and thinking will be measured over several weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
synbiotic supplement (Probio-Tec ABCG)
What this could lead to
If it works, this could point toward a simple, safe add-on treatment to help control schizophrenia symptoms.
What could go wrong
This is a small, early-phase trial (68 people) testing a supplement, not a new drug. The effect may be small or no better than placebo.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Sheppard Pratt Health System
RECRUITINGBatlimore, Maryland, 21285, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••