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Could daily swallowing exercises ease a harsh side effect of cancer treatment?

NCT ID NCT07795294

Symptom relief Sponsor: Delta University for Science and Technology Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 31, 2026 · Last updated Sep 01, 2026 · Updated 1 time

Summary

This trial tests whether a structured swallowing rehabilitation program can improve swallowing function, reduce jaw stiffness, and ease pain in people with head and neck cancer. Researchers will randomly assign 80 patients who have had radiation or chemoradiotherapy to either the exercise program or standard care. The program includes specific swallowing maneuvers and jaw stretching exercises done twice daily. The study measures changes in swallowing difficulty and jaw tightness using standard questionnaires.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
A structured swallowing rehabilitation program with exercises such as the Mendelsohn maneuver, effortful swallow, Masako technique, tongue strengthening, and jaw stretching, done twice daily.
What this could lead to
If it works, this program could offer a simple, drug-free way to improve swallowing and reduce jaw stiffness and pain for people treated for head and neck cancer.
What could go wrong
The trial is small and early, and results may not apply to everyone. Exercises require daily effort, and some patients may find them hard to keep up.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Both genders * Aged 20-60 years * Patients receiving chemoradiotherapy * Patients having a history of head and neck cancer * Patients who had received previous radiation therapy for head and neck cancer Exclusion Criteria: * Patients who had neurological or psychiatric problems * Patients who had dysphagia for a reason other than cancer

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Conditions

The condition(s) this trial relates to.

Deglutition Disorders head and neck cancer Head and Neck Neoplasms Trismus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Head and neck cancer (H&N)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • National Cancer Institute, Cairo University

    Cairo, Egypt

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