Surgery offers new hope for chronic pain sufferers

NCT ID NCT07263256

First seen Dec 16, 2025 · Last updated Jun 23, 2026 · Updated 35 times

Summary

This study tested surgery to treat Complex Regional Pain Syndrome (CRPS) in the upper limb. 74 adults with CRPS who had not improved with other treatments received either nerve decompression or correction of a specific structural problem. Pain levels were measured before surgery, at 10-12 days, and at three months to see how much and how quickly pain changed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Hospital Nové Město Na Moravě

    Nové Město na Moravě, Czech Republic, 592 31, Czechia

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Surgery (median nerve decompression and lesion-specific correction)

What this could lead to

If successful, this surgical approach could offer a new way to reduce pain for people with Complex Regional Pain Syndrome who haven't improved with other treatments.

What could go wrong

This is a small, completed study without a control group, so results may not apply to everyone. Surgery carries risks like infection or nerve damage, and pain relief may not last.

Conditions

The condition(s) this trial relates to.

Charcot-Marie-Tooth disease Chronic Pain complex regional pain syndrome complex regional pain syndrome type 1 nerve compression syndrome neuralgia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.