Scientists probe why Women's blood vessels change with age
NCT ID NCT06417177
First seen Jun 24, 2026 · Last updated Jun 24, 2026
Summary
This study looks at how aging and menopause change the way blood vessels widen in response to low oxygen. Researchers will give healthy women either a placebo, a beta-blocker (propranolol), or a bladder medication (gemtesa) to see how these drugs affect blood flow. The goal is to better understand the role of certain receptors in blood vessel function across different life stages.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Missouri-Columbia
RECRUITINGColumbia, Missouri, 65211, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Propranolol and Gemtesa (oral drugs) and placebo
What this could lead to
If successful, this could help scientists understand why blood vessels react differently to low oxygen as women age, potentially guiding future treatments for vascular health.
What could go wrong
This is an early-phase study with only 75 participants, so results may not apply to all women. The drugs used are for research purposes only and are not intended to treat any condition.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.