New wrinkle treatment combo shows promise in early trial
NCT ID NCT06834789
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage study tested whether a new drug called AGN-151586 can be safely combined with BOTOX to treat moderate to severe frown lines between the eyebrows. Researchers monitored 132 healthy adults for side effects and immune responses after a single treatment session. The goal was to check safety and see if the combination works better than BOTOX alone.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Austin Institute for Clinical Research - Pflugerville /ID# 270834
Pflugerville, Texas, 78660, United States
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Eye Research Foundation /ID# 270827
Newport Beach, California, 92663, United States
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Investigate MD /ID# 270771
Scottsdale, Arizona, 85260, United States
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Marcus Facial Plastic Surgery /ID# 270770
Redondo Beach, California, 90277, United States
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Skin Research Institute LLC /ID# 270831
Coral Gables, Florida, 33146-1837, United States
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SkinDC /ID# 270932
Arlington, Virginia, 22209, United States
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Skincare Physicians /ID# 271018
Chestnut Hill, Massachusetts, 02467, United States
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Wilmington Dermatology Center /ID# 270828
Wilmington, North Carolina, 28403, United States