New combo treatment targets Crow's feet and hollow eyes

NCT ID NCT07398755

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study observed 29 adults receiving a combination of botulinum toxin (Letybo), hyaluronic acid filler (Saypha Volume Plus), and polynucleotide injections (Philart Eye) around the eyes. The goal was to see how well this holistic approach reduces wrinkles and restores volume over 22 weeks. Researchers measured skin changes and patient satisfaction at several follow-up visits.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

botulinum toxin A, hyaluronic acid filler, and polynucleotide

What this could lead to

If successful, this could confirm that a combination of these injectable treatments safely improves wrinkles and volume loss around the eyes for several months.

What could go wrong

This is a small, completed observational study with only 29 participants. Results may not apply to everyone, and the effects are temporary, requiring repeat treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • YUVELL

    Vienna, State of Vienna, 1010, Austria