New drug combo targets brain tumor marker before surgery
NCT ID NCT03343197
First seen Feb 20, 2026 · Last updated Apr 28, 2026 · Updated 8 times
Summary
This study tested two experimental drugs, AG-120 and AG-881, in 49 adults with a recurrent, slow-growing brain tumor called IDH1 mutant low-grade glioma. Participants took the drugs for a short time before their scheduled surgery to see if the drugs could lower a substance called 2-HG in the tumor. The main goal was to measure 2-HG levels in the removed tumor tissue and check for side effects.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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United States, California
Los Angeles, California, 90024, United States
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United States, California
San Francisco, California, 94143, United States
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United States, Massachusetts
Boston, Massachusetts, 02215, United States
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United States, New York
New York, New York, 10065, United States
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United States, North Carolina
Durham, North Carolina, 27710, United States
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United States, Texas
Dallas, Texas, 75390, United States
Conditions
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