Can a clot-busting procedure help stroke patients with existing disabilities?

NCT ID NCT05911568

First seen Sep 30, 2025 · Last updated May 20, 2026 · Updated 27 times

Summary

This study looks at whether a procedure called endovascular thrombectomy (EVT) can help people who have a stroke but already had a moderate-to-severe disability before the stroke. About 1,060 adults with a large blood vessel blockage in the brain will be randomly assigned to get EVT plus standard care or just standard care. The goal is to see if EVT improves recovery or reduces death compared to medical management alone.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

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  • Contact

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Locations

  • Baptist Memorial Hospital

    RECRUITING

    Memphis, Tennessee, 38120, United States

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  • Barnes Jewish Hospital

    RECRUITING

    Saint Loius, Missouri, 63110, United States

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  • Boston Medical Center

    RECRUITING

    Boston, Massachusetts, 02118, United States

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  • Columbia University

    RECRUITING

    New York, New York, 10032, United States

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  • Emory University

    RECRUITING

    Atlanta, Georgia, 30322, United States

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  • Hartford Health Hospital

    RECRUITING

    Hartford, Connecticut, 06106, United States

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  • HonorHealth

    RECRUITING

    Phoenix, Arizona, 85013, United States

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  • Icahn School of Medicine at Mount Sinai

    RECRUITING

    New York, New York, 10029, United States

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  • Kaiser Permanente Los Angeles Medical Center

    RECRUITING

    Los Angeles, California, 90027, United States

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  • New York University

    RECRUITING

    Brooklyn, New York, 11220, United States

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  • Providence St. Vincent Medical Center

    RECRUITING

    Portland, Oregon, 97225, United States

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  • Standford

    RECRUITING

    Palo Alto, California, 94305, United States

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  • Swedish Medical Center

    RECRUITING

    Englewood, Colorado, 80113, United States

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  • University of California at Los Angeles

    RECRUITING

    Los Angeles, California, 90095, United States

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  • University of Chicago

    RECRUITING

    Chicago, Illinois, 60637, United States

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  • University of Cincinnati Medical Center

    RECRUITING

    Cincinnati, Ohio, 45219, United States

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  • University of Cincinnati San Diego

    RECRUITING

    San Diego, California, 92121, United States

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  • University of Louisville

    RECRUITING

    Louisville, Kentucky, 40202, United States

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  • University of Miami

    RECRUITING

    Miami, Florida, 33125, United States

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  • University of Pittsburgh Medical Center

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

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  • University of Texas at Austin

    RECRUITING

    Austin, Texas, 78712, United States

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  • University of Washington

    RECRUITING

    Seattle, Washington, 98104, United States

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  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

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  • West Virginia University

    RECRUITING

    Morgantown, West Virginia, 26506, United States

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  • Yale University

    RECRUITING

    New Haven, Connecticut, 06510, United States

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Conditions

Explore the condition pages connected to this study.