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New hope for stroke prevention in heart patients who Can't use standard meds

NCT ID NCT07430956

Recruiting now Disease control Sponsor: Regeneron Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests two experimental drugs, REGN7508 and REGN9933, to prevent strokes in people with atrial fibrillation (an irregular heartbeat) who cannot or choose not to take standard blood thinners. About 2,628 participants will receive one of the drugs or a placebo to see if they reduce the risk of stroke or blood clots. The goal is to find a safer option for those at high risk of bleeding.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation pulmonary embolism thrombotic disease venous thromboembolism ischemic stroke prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION (AF)

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AA Medical Research Center (MRC)

    RECRUITING

    Flint, Michigan, 48504, United States

  • AnMed Health

    RECRUITING

    Anderson, South Carolina, 29621, United States

  • Cardiology Associates Medical Group

    RECRUITING

    Ventura, California, 93003, United States

  • Clinical Site Partners, LLC DBA Flourish Research

    RECRUITING

    Winter Park, Florida, 32789, United States

  • Interventional Cardiology Medical Group

    RECRUITING

    West Hills, California, 91307, United States

  • K&R Research LLC

    RECRUITING

    Marion, Ohio, 43302, United States

  • Mission Cardiovascular Research Institute

    RECRUITING

    Fremont, California, 94538, United States

  • Monroe Research, LLC

    RECRUITING

    West Monroe, Louisiana, 71291, United States

  • NSC Research, Inc

    RECRUITING

    Johns Creek, Georgia, 30024, United States

  • National Institute of California Heart and Vein Specialists

    RECRUITING

    Huntington Beach, California, 92648, United States

  • PharmaTex Research

    RECRUITING

    Amarillo, Texas, 79106, United States

  • Profound Research LLC at Southern California Heart Specialists

    RECRUITING

    Pasadena, California, 91105, United States

  • Profound Research, Millennium Cardiology

    RECRUITING

    Farmington Hills, Michigan, 48334, United States

  • SEC Clinical Research

    RECRUITING

    Dothan, Alabama, 36305, United States

  • Sec Clinical Research

    RECRUITING

    Pensacola, Florida, 32503, United States

  • South Florida Research Organization LLC

    RECRUITING

    Medley, Florida, 33166, United States

  • Southwest Family Medicine Associates

    RECRUITING

    Dallas, Texas, 75235, United States

  • Texas Institute of Cardiology PA

    RECRUITING

    McKinney, Texas, 75071, United States

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