New hope for AF patients: needle-based stroke prevention without daily pills

NCT ID NCT07430956

First seen Feb 25, 2026 · Last updated May 29, 2026 · Updated 8 times

Summary

This study tests two experimental drugs (REGN7508 and REGN9933) to prevent strokes in about 2,600 people with atrial fibrillation (an irregular heartbeat) who cannot or choose not to take standard blood thinners. The drugs are designed to block a clotting factor to reduce stroke risk. Participants will receive either one of the drugs or a placebo, and researchers will monitor for strokes, bleeding events, and side effects over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AA Medical Research Center (MRC)

    RECRUITING

    Flint, Michigan, 48504, United States

  • Cardiology Associates Medical Group

    RECRUITING

    Ventura, California, 93003, United States

  • K&R Research LLC

    RECRUITING

    Marion, Ohio, 43302, United States

  • Profound Research LLC at Southern California Heart Specialists

    RECRUITING

    Pasadena, California, 91105, United States

  • SEC Clinical Research

    RECRUITING

    Dothan, Alabama, 36305, United States

Conditions

Explore the condition pages connected to this study.