Can stress shorten life in brain cancer? new study investigates

NCT ID NCT05431348

Completed Knowledge-focused Sponsor: Maastricht Radiation Oncology Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at whether stress and exercise levels influence survival and quality of life in 42 people with glioblastoma, a severe brain cancer. Participants wore a smartwatch to track heart rate, sleep, and activity, and filled out questionnaires on stress and fatigue. The goal was to see if stress markers like cortisol and heart rate are linked to how long patients live after chemoradiation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If stress is confirmed as a key factor, future treatments might include stress-reduction programs to improve outcomes.
What could go wrong: This is a small, observational study with only 42 participants. It cannot prove cause and effect, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

astrocytoma, IDH-mutant, grade 4 diffuse astrocytoma glioblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLIOBLASTOMA (GBM)

Contacts and locations

Locations

Maastricht Radiation Oncology (Maastro)

Maastricht, Limburg, 6229ET, Netherlands
Verbeeten Insitute Tilburg

Tilburg, Netherlands

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