Freezing away AF: new study tracks 3-Year success of cryoablation

NCT ID NCT05227053

Recruiting now Disease control Sponsor: Medtronic Cardiac Ablation Solutions Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 23, 2026 · Updated 3 times

Summary

This study follows 200 people with paroxysmal atrial fibrillation (AF) who undergo a procedure using a freezing catheter to isolate the pulmonary veins. The goal is to see how many remain free from AF, atrial flutter, or atrial tachycardia for up to 3 years, and to track safety events over 12 months. It is an observational, post-approval study, meaning the device is already approved and in use.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Arctic Front™ cardiac cryoablation catheter (a device that freezes heart tissue to stop abnormal electrical signals)
What this could lead to: If successful, this could confirm that cryoablation is a safe and effective long-term option for controlling paroxysmal atrial fibrillation.
What could go wrong: This is an observational study, not a randomized trial, so results may be less definitive. Risks include rare but serious complications like heart damage or stroke from the procedure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation paroxysmal atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PAROXYSMAL ATRIAL FIBRILLATION

Contacts and locations

Locations

Alaska Heart Institute
ACTIVE_NOT_RECRUITING

Anchorage, Alaska, 99508, United States
BayCare Medical Group Cardiology
RECRUITING

Clearwater, Florida, 33756, United States
Cardiology Associates of Fairfield County
RECRUITING

Stamford, Connecticut, 06905-5522, United States
Heart Rhythm Solutions
RECRUITING

Davie, Florida, 33328, United States
Henry Ford Heart & Vascular
RECRUITING

Detroit, Michigan, 48202-2608, United States
Iowa Heart
RECRUITING

West Des Moines, Iowa, 50266, United States
MedStar Washington Hospital Center
RECRUITING

Washington D.C., District of Columbia, 20010, United States
Our Lady of the Lake
WITHDRAWN

Baton Rouge, Louisiana, 70808, United States
Southcoast Health System
RECRUITING

North Dartmouth, Massachusetts, 02747, United States
Stern Cardiovascular Foundation
RECRUITING

Germantown, Tennessee, 38138, United States
Texas Health Research and Education Institute
RECRUITING

Dallas, Texas, 75231, United States
The Lindner Research Center
RECRUITING

Cincinnati, Ohio, 45219, United States
University of Tennessee Methodist Physicians
WITHDRAWN

Memphis, Tennessee, 38104-6638, United States

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