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Could simple guidelines cut ICU anemia deaths?

NCT ID NCT07771192

Disease control Sponsor: University Hospital, Angers Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 18, 2026 · Last updated Aug 19, 2026 · Updated 1 time

Summary

This study tests whether providing hospitals with a structured program to follow anemia prevention and management guidelines can lower death rates in intensive care unit (ICU) patients. The trial will involve about 5,760 adults who stay in the ICU for at least two days and have organ failure. Each hospital will start the program at a randomly assigned time, allowing researchers to compare outcomes before and after implementation.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Implementation of recommendations for anemia prevention and management in intensive care units
What this could lead to
If successful, this could establish a practical approach to reduce hospital deaths and improve recovery for critically ill patients with anemia.
What could go wrong
The study is pragmatic and relies on real-world implementation, which may vary across centers. It may not show a clear benefit on mortality, and results may not apply to all ICU settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 5,760 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Mar 2028

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

adult patients hospitalized in intensive care for ≥2 days

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Length of stay in intensive care is ≥ 2 days * The patient has at least one organ failure lasting 24 hours or more (catecholamine infusion and/or mechanical ventilation (invasive or NIV \> 6 hours/day)) * No objection to data collection (patient or relative) Exclusion Criteria: * Terminally ill patient with limited active treatment options within 72 hours of admission.

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Conditions

The condition(s) this trial relates to.

anemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anemia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    27 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • CH de LAVAL

    Laval, France

  • CHRU BREST SITE HOPITAL CAVALE BLANCHE, réanimation chirurgicale

    Brest, France

  • CHRU BREST SITE HOPITAL CAVALE BLANCHE, réanimation médicale

    Brest, France

  • CHU Grenoble-HOPITAL SUD - CHU38

    Grenoble, France

  • CHU LA MILETRIE, réanimation neurochirurgicale

    Poitiers, France

  • Centre Hospitalier Du Mans

    Le Mans, France

  • Ch Chartres Louis Pasteur-Le Coudray

    Chartres, France

  • Ch Victor Dupouy

    Argenteuil, France

  • Ch de Cholet

    Cholet, France

  • Chru Nancy - Hopitaux de Brabois

    Nancy, France

  • Chru Rennes Site Pontchaillou

    Rennes, France

  • Chru Trousseau - Chambray

    Tours, France

  • Gcs Irm Beaujon Moleculaire Act, Ap-Hp

    Paris, France

  • HOPITAL GABRIEL MONTPIED - CHU63, Réanimation Médico-Chrirugicale

    Clermont-Ferrand, France

  • HOPITAL GABRIEL MONTPIED - CHU63, Réanimation Neurochirurgicale

    Clermont-Ferrand, France

  • HU PITIE SALPETRIERE APHP, Réanimation Chirurgicale

    Paris, France

  • HU PITIE SALPETRIERE APHP, Réanimation Neuro-Chirurgicale

    Paris, France

  • Hopital Cochin Tarnier Aphp

    Paris, France

  • Hopital Haut-Leveque - Chu

    Talence, France

  • Hopital Laenec, CHU Nantes

    Nantes, France

  • Hopital Purpan Chu Toulouse

    Toulouse, France

  • Hopital St Eloi Chu Montpellier

    Montpellier, France

  • Hopital de Hautepierre

    Strasbourg, France

  • Hu Est Parisien Site St Antoine Aphp

    Paris, France

  • Hu Paris Nord Site Bichat Aphp

    Paris, France

  • Hôtel Dieu, CHU Nantes

    Nantes, France

  • réanimation médicale CHU ANGERS

    Angers, 49000, France

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