A simple test could spot who will develop stomach cancer

NCT ID NCT05782465

Ongoing Diagnosis Sponsor: National University Hospital, Singapore Source: ClinicalTrials.gov ↗

First seen Aug 07, 2026 · Last updated Aug 07, 2026

Summary

This study is testing whether a customized molecular test can identify which people with intestinal metaplasia—a condition that can precede stomach cancer—are at very high risk of developing the disease. Researchers will collect blood and stomach tissue samples from 500 adults aged 50 to 75 and follow them over several years to see if the test's predictions hold true. If it works, the test could help doctors focus surveillance on those who need it most and avoid unnecessary procedures for others.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: A molecular test using blood and stomach biopsy samples to assess stomach cancer risk
What this could lead to: If successful, this test could help doctors focus stomach cancer surveillance on those at highest risk, while reducing unnecessary procedures for others.
What could go wrong: The test is still being validated, and it may not accurately predict risk in all patients. It is not yet a proven tool for routine use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

gastric intestinal metaplasia gastric neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

STOMACH NEOPLASM

Contacts and locations

Locations

National Taiwan University Hospital

Taipei, Taiwan
National University Hospital

Singapore, 119074, Singapore
Nihon University School of Medicine

Tokyo, Japan
Singapore General Hospital

Singapore, 169608, Singapore
Stanford University

Stanford, California, 94305, United States
Tan Tock Seng Hospital, Singapore

Singapore, 308433, Singapore
The Chinese University of Hong Kong

Hong Kong, Hong Kong
Yonsei University, Republic of Korea

Seoul, South Korea

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