New hope for stiff person syndrome: drug trial aims to ease muscle stiffness and improve walking

This study tests a medicine called IGIV 10% (a type of antibody treatment) against a placebo in 38 adults aged 18-70 with Stiff Person Syndrome, a rare condition causing muscle stiffness and spasms. The main goal is to see if the drug helps people walk faster (measured by a 25-foot walk test) and reduces stiffness over 24 weeks. Participants will receive either the drug or a placebo through an IV, and researchers will track improvements and side effects.