New hope for stiff person syndrome: drug trial aims to ease muscle stiffness and improve walking

NCT ID NCT07552987

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a medicine called IGIV 10% (a type of antibody treatment) against a placebo in 38 adults aged 18-70 with Stiff Person Syndrome, a rare condition causing muscle stiffness and spasms. The main goal is to see if the drug helps people walk faster (measured by a 25-foot walk test) and reduces stiffness over 24 weeks. Participants will receive either the drug or a placebo through an IV, and researchers will track improvements and side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

autoimmune disease nervous system disorder stiff-person syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••