New stent shows promise for blocked brain arteries

NCT ID NCT05316311

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a special stent designed to open severely narrowed brain arteries in 194 people with symptomatic intracranial atherosclerosis. The goal was to see if the stent is safe and effective at keeping arteries open for at least 12 months. Researchers measured how often the artery narrowed again inside the stent and whether the procedure was technically successful.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CERENOVUS ENTERPRISE 2 intracranial stent

What this could lead to

If successful, this stent could offer a safe way to reopen blocked brain arteries and reduce stroke risk in high-risk patients.

What could go wrong

This was a single-arm study without a comparison group, so results may not prove the stent is better than standard care. The stent may also narrow again over time.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cerebral artery stenosis intracranial arteriosclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Central Hospital Affiliated to Shandong First Medical University (Jinan Central Hospital)

    Jinan, China

  • First Affiliated Hospital, Harbin Medical University

    Harbin, China

  • Haikou People's Hospital

    Haikou, China

  • Huashan Hospital Fudan University

    Shanghai, China

  • Nanjing Drum Tower Hospital

    Nanjing, China

  • Ningbo First Hospital

    Ningbo, China

  • Qilu Hospital of Shandong University

    Jinan, China

  • Shandong Provincial Hospital

    Jinan, China

  • The First Affiliated Hospital of Xi'an Jiaotong University

    Xi'an, China

  • The First Affiliated Hospital of Zhengzhou University

    Zhengzhou, China

  • The Second Affiliated Hospital of Xi'an Jiaotong University

    Xi'an, China

  • Wenzhou Central Hospital

    Wenzhou, China

  • West China Hospital of Sichuan University

    Chengdu, China

  • Xuanwu Hospital, Capital Medical University

    Beijing, China