New stent shows promise for blocked brain arteries

NCT ID NCT05316311

Completed Disease control Sponsor: Medos International SARL Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Aug 07, 2026 · Updated 2 times

Summary

This study tested a special stent designed to open severely narrowed brain arteries in 194 people with symptomatic intracranial atherosclerosis. The goal was to see if the stent is safe and effective at keeping arteries open for at least 12 months. Researchers measured how often the artery narrowed again inside the stent and whether the procedure was technically successful.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: CERENOVUS ENTERPRISE 2 intracranial stent
What this could lead to: If successful, this stent could offer a safe way to reopen blocked brain arteries and reduce stroke risk in high-risk patients.
What could go wrong: This was a single-arm study without a comparison group, so results may not prove the stent is better than standard care. The stent may also narrow again over time.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cerebral artery stenosis intracranial arteriosclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INTRACRANIAL ATHEROSCLEROSIS

Contacts and locations

Locations

Central Hospital Affiliated to Shandong First Medical University (Jinan Central Hospital)

Jinan, China
First Affiliated Hospital, Harbin Medical University

Harbin, China
Haikou People's Hospital

Haikou, China
Huashan Hospital Fudan University

Shanghai, China
Nanjing Drum Tower Hospital

Nanjing, China
Ningbo First Hospital

Ningbo, China
Qilu Hospital of Shandong University

Jinan, China
Shandong Provincial Hospital

Jinan, China
The First Affiliated Hospital of Xi'an Jiaotong University

Xi'an, China
The First Affiliated Hospital of Zhengzhou University

Zhengzhou, China
The Second Affiliated Hospital of Xi'an Jiaotong University

Xi'an, China
Wenzhou Central Hospital

Wenzhou, China
West China Hospital of Sichuan University

Chengdu, China
Xuanwu Hospital, Capital Medical University

Beijing, China

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