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Stem cell shot could save legs from amputation

NCT ID NCT05854641

Recruiting now Disease control Sponsor: Cell Biopeutics Resources Sdn Bhd Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether injecting donor stem cells (Stempeucel) into the leg muscle can help people with critical limb ischemia, a severe form of peripheral artery disease. Ten Malaysian patients who cannot have surgery or angioplasty will receive the stem cells and be followed for one year. Researchers will measure changes in pain, ulcer size, walking distance, and amputation rates.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Stempeucel (donor stem cells injected into the leg muscle)
What this could lead to
If it works, this could point toward a new way to reduce pain, heal ulcers, and prevent amputation in people with severe leg artery disease.
What could go wrong
This is a very small, early feasibility study with only 10 patients, so results may not apply widely. Stem cell treatments can cause inflammation or other side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Chronic Limb-Threatening Ischemia limb ischemia peripheral arterial disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CRITICAL LIMB ISCHEMIA PERIPHERAL ARTERIAL DISEASE

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Hospital Canselor Tunku Mukhriz

    RECRUITING

    Kuala Lumpur, 56000, Malaysia

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