Stem cells shot into penis aim to restore erections after prostate surgery

NCT ID NCT01089387

Completed Disease control Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial tested whether injecting a man's own bone marrow stem cells into the penis could help restore erections after prostate cancer surgery. The study included 18 men who had normal erections before surgery but developed erectile dysfunction due to blood vessel damage. Researchers tested four different doses to find the safest and most promising one.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: bone marrow stem cells (mononucleated cells)
What this could lead to: If it works, this could point toward a treatment for erectile dysfunction after prostate removal, potentially restoring natural erections without lifelong medication.
What could go wrong: This is a very small, early-phase trial (18 men) testing safety and dosing. It may not lead to an effective treatment, and risks include priapism or local inflammation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

erectile dysfunction prostate cancer prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ERECTILE DYSFUNCTION PROSTATE CANCER

Contacts and locations

Locations

CHU Henri Mondor-Albert Chenevier-Centre Intercommunal de Créteil

Créteil, 94101, France

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