Stem cell transplant or drug combo: which works better for myeloma?
NCT ID NCT01745588
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested two ways to treat multiple myeloma that has come back or stopped responding to treatment. All 23 participants first received a combination of clarithromycin, pomalidomide, and dexamethasone. Then, half got a stem cell transplant followed by pomalidomide, while the other half continued the drug combo. The goal was to see which approach better controls the disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
pomalidomide, clarithromycin, dexamethasone, and autologous stem cell transplant
What this could lead to
If successful, this could help doctors choose the best treatment sequence for relapsed multiple myeloma, potentially improving disease control.
What could go wrong
This is a small, early-phase study with only 23 participants, so results may not apply to everyone. Both treatments have side effects, and the disease may still progress.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Memorial Sloan Kettering Cancer Center
Basking Ridge, New Jersey, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Memorial Sloan Kettering Cancer Center @ Suffolk
Commack, New York, 11725, United States
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Memorial Sloan Kettering Cancer Center at Mercy Medical Center
Rockville Centre, New York, 11570, United States
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Memorial Sloan Kettering Cancer Center at Phelps Memorial Hospital Center
Sleepy Hollow, New York, 10591, United States
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Memorial Sloan Kettering West Harrison
Harrison, New York, 10604, United States
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North Shore LIJ
New Hyde Park, New York, 11040, United States
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Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey, 08903, United States
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SUNY Upstate Medical University
Syracuse, New York, United States
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Weill Medical College of Cornell University
New York, New York, United States