Can your own stem cells repair MS nerve damage? new trial aims to find out

NCT ID NCT04749667

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial tests whether a patient's own bone marrow stem cells, injected into the spinal fluid, can repair nerve damage caused by progressive multiple sclerosis. The study involves 18 adults with secondary or primary progressive MS. Researchers will measure changes in nerve signals, vision, and MRI scans to see if the treatment is safe and shows any signs of repair.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

patient's own bone marrow stem cells (mesenchymal stem cells)

What this could lead to

If it works, this could point toward a treatment that repairs nerve damage and slows or reverses disability in progressive multiple sclerosis.

What could go wrong

This is a very early, small study (18 people) testing safety and basic effectiveness. Many early-stage stem cell trials do not lead to approved treatments, and there are risks from the procedure itself.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic progressive multiple sclerosis multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Akershus university hospital

    Lørenskog, Akershus, Norway

  • Haukeland University Hospital

    Bergen, Vestland, Norway

  • St.Olav university hospital

    Trondheim, Trøndelag, Norway

  • University hospital of North Norway

    Tromsø, Troms Og Finnmark, Norway