Umbilical cord stem cells tested for liver cirrhosis – early results promising?

NCT ID NCT05331872

Completed Disease control Sponsor: Vinmec Research Institute of Stem Cell and Gene Technology Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tested whether stem cells from donated umbilical cords are safe for people with liver cirrhosis. Twenty adults received an infusion of these cells and were monitored for a year. The main goal was to check for side effects, but researchers also looked for signs of improved liver function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: human umbilical cord-derived mesenchymal stem cells
What this could lead to: If it works, this could point toward a new cell-based treatment to improve liver function in cirrhosis patients.
What could go wrong: This is a very early Phase 1 trial with only 20 people, so it mainly checks safety, not effectiveness. The stem cells may not improve liver function, and there are risks like infection or allergic reactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LIVER CIRRHOSIS

Contacts and locations

Locations

Vinmec Research Institute of Stem Cell and Gene Technology

Hanoi, Hanoi, 100000, Vietnam

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