New stem cell combo aims to fight stubborn childhood cancers

NCT ID NCT06625190

First seen Oct 31, 2025 · Last updated May 16, 2026 · Updated 23 times

Summary

This study tests a stem cell transplant that removes certain immune cells (alpha/beta T cells and CD19+ B cells) and adds a drug called zoledronic acid. The goal is to help the donor cells attack the tumor without causing severe side effects. It is for children and young adults aged 6 months to 25 years with relapsed or treatment-resistant solid tumors like neuroblastoma, sarcoma, and others. The study will check safety and whether this approach improves survival rates.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Florida

    RECRUITING

    Gainesville, Florida, 32610, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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