New combo therapy aims to tame tough Crohn's cases
NCT ID NCT03219359
First seen Nov 05, 2025 · Last updated May 14, 2026 · Updated 27 times
Summary
This study tests whether adding the drug vedolizumab after a stem cell transplant can help people with severe Crohn's disease stay in remission longer. About 50 adults with active Crohn's who have not responded to standard treatments will receive a stem cell transplant followed by vedolizumab. The goal is to see if this approach improves remission rates one year after transplant.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Icahn School of Medicine at Mount Sinai
RECRUITINGNew York, New York, 10029, United States
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