Own stem cells tested to fight liver scarring in 700 patients

NCT ID NCT05080465

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed phase 3 study followed 700 people with liver cirrhosis caused by hepatitis B, C, or fatty liver disease. Researchers took a small amount of bone marrow from each patient, processed it to collect stem cells, and infused those cells back into the patient. The goal was to check safety and see if the treatment could improve liver stiffness and blood markers of liver function over the long term.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

autologous bone marrow mesenchymal stem cells

What this could lead to

If successful, this could offer a way to slow or improve liver cirrhosis using a patient's own stem cells, potentially reducing the need for a liver transplant.

What could go wrong

This is a follow-up study, not a new treatment test, and results may not confirm lasting benefit. Stem cell therapy carries risks like infection or immune reactions, and cirrhosis is a complex disease that may not respond.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver Digestive System Diseases Fibrosis liver disorder Pathologic Processes

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Institute of Bio-Stem Cell Rehabilitation

    Kharkiv, Ukraine