Own stem cells tested to fight liver scarring in 700 patients
NCT ID NCT05080465
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed phase 3 study followed 700 people with liver cirrhosis caused by hepatitis B, C, or fatty liver disease. Researchers took a small amount of bone marrow from each patient, processed it to collect stem cells, and infused those cells back into the patient. The goal was to check safety and see if the treatment could improve liver stiffness and blood markers of liver function over the long term.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- autologous bone marrow mesenchymal stem cells
- What this could lead to
- If successful, this could offer a way to slow or improve liver cirrhosis using a patient's own stem cells, potentially reducing the need for a liver transplant.
- What could go wrong
- This is a follow-up study, not a new treatment test, and results may not confirm lasting benefit. Stem cell therapy carries risks like infection or immune reactions, and cirrhosis is a complex disease that may not respond.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Institute of Bio-Stem Cell Rehabilitation
Kharkiv, Ukraine
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