Could your own stem cells repair a failing heart?

NCT ID NCT03572660

Ongoing Disease control Sponsor: Barts & The London NHS Trust Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This phase 2 trial is testing whether a patient's own bone marrow stem cells can improve heart function and ease symptoms in people with dilated cardiomyopathy and heart failure. Twenty participants will have stem cells collected from their hip and then infused into their heart arteries while a mini heart pump supports the heart. The study will measure changes in heart pumping ability, exercise capacity, and symptoms over 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: patient's own bone marrow stem cells and G-CSF
What this could lead to: If it works, this could point toward a new way to improve heart function and reduce symptoms in people with dilated cardiomyopathy who have few other options.
What could go wrong: This is a small, early-phase trial with only 20 participants, so results may not apply to everyone. The procedure carries risks from the mini heart pump and stem cell infusion, and the treatment may not improve heart function.

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Conditions

The condition(s) this trial relates to.

dilated cardiomyopathy heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DILATED CARDIOMYOPATHY

Contacts and locations

Locations

St Bartholomew's Hospital

London, EC1A 7BE, United Kingdom

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