Nerve block aimed at calming POTS symptoms in small stanford trial

NCT ID NCT06953661

Not yet recruiting Symptom relief Sponsor: Stanford University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study from Stanford tests whether a stellate ganglion block (a nerve block in the neck) can reduce symptoms of Postural Tachycardia Syndrome (POTS). Twenty adults with POTS will receive either the nerve block or a sham injection. Researchers will track changes in autonomic symptoms and heart rate over follow-up visits. This is early research to see if the procedure is worth studying further.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: stellate ganglion block (nerve block with ropivacaine)
What this could lead to: If it works, this could point toward a new way to manage POTS symptoms like dizziness and rapid heart rate.
What could go wrong: This is a very small, early pilot study with only 20 people. It may not show clear benefit, and nerve blocks carry risks like bleeding or infection.

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Conditions

The condition(s) this trial relates to.

postural orthostatic tachycardia syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POSTURAL TACHYCARDIA SYNDROME

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Stanford University

Stanford, California, 94305, United States
Stanford University School of Medicine

Stanford, California, 94304, United States

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