Massive study tests common pill to ward off dementia in seniors

NCT ID NCT04262206

Recruiting now Prevention Sponsor: Duke University Source: ClinicalTrials.gov ↗

Summary

This large study aims to see if taking a daily cholesterol-lowering statin pill (atorvastatin) can help prevent dementia, disability, and death in healthy adults aged 75 and older. About 20,000 participants will be randomly assigned to take either the statin or a placebo (inactive pill) for up to five years. The goal is to find out if this widely available medication can help older adults maintain their independence and cognitive health.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

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Locations

Albert Einstein College of Medicine
RECRUITING

The Bronx, New York, 10461, United States

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Allina Health
ACTIVE_NOT_RECRUITING

Minneapolis, Minnesota, 55407, United States
Asheville VA-Charles George VA Medical Center
RECRUITING

Asheville, North Carolina, 28805, United States

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Atlanta VA Medical Center
RECRUITING

Atlanta, Georgia, 30033, United States

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Atrium Health
RECRUITING

Charlotte, North Carolina, 28207, United States

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Bay Pines VA
RECRUITING

Bay Pines, Florida, 33744, United States

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Baylor Scott and White Medical Center
RECRUITING

Dallas, Texas, 75210, United States

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Birmingham VA
RECRUITING

Birmingham, Alabama, 35233, United States

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Bronx VA Medical Center
WITHDRAWN

The Bronx, New York, 10468, United States
Case Western Reserve University
RECRUITING

Cleveland, Ohio, 44106, United States

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Cedars-Sinai Medical Center
NOT_YET_RECRUITING

Los Angeles, California, 90048, United States

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Charleston VA Medical Center
RECRUITING

Charleston, South Carolina, 29401, United States

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Chicago VA Medical Center/Jesse Brown VA
WITHDRAWN

Chicago, Illinois, 60612, United States
Cincinnati VA Medical Center
RECRUITING

Cincinnati, Ohio, 45220, United States

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Clarksburg VA Medical Center
WITHDRAWN

Clarksburg, West Virginia, 26301, United States
Columbia VA Health Care/Dorn VA Medical Center
RECRUITING

Columbia, South Carolina, 29209, United States

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Corporal Michael J. Crescenz VA Medical Center-Philadelphia VA
WITHDRAWN

Philadelphia, Pennsylvania, 19104, United States
Dallas VA Medical Center
RECRUITING

Dallas, Texas, 75216, United States

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Dayton VA Medical Center
RECRUITING

Dayton, Ohio, 45428, United States

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Doctors Hospital at Renaissance
RECRUITING

Edinburg, Texas, 78539, United States

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Duke University
RECRUITING

Durham, North Carolina, 27710, United States

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Duke University - Kannapolis
RECRUITING

Kannapolis, North Carolina, 28081, United States

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Durham VA Medical Center
RECRUITING

Durham, North Carolina, 27705, United States

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Emory University
RECRUITING

Atlanta, Georgia, 30322, United States

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Essentia Health
RECRUITING

Duluth, Minnesota, 55805, United States

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Fresno VA Medical Center
RECRUITING

Fresno, California, 93703, United States

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Gainesville VA Medical Center
RECRUITING

Gainesville, Florida, 32608, United States

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Hines VA Medical Center
RECRUITING

Hines, Illinois, 60141, United States

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Indianapolis VA Medical Center
RECRUITING

Indianapolis, Indiana, 46202, United States

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Intermountain
RECRUITING

Murray, Utah, 84107, United States

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Johns Hopkins University
RECRUITING

Baltimore, Maryland, 21287, United States

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Kansas City VA Medical Center
RECRUITING

Kansas City, Kansas, 64128, United States

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Little Rock VA Medical Center
RECRUITING

Little Rock, Arkansas, 72114, United States

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Long Beach VA Medical Center
RECRUITING

Long Beach, California, 90822, United States

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Louisville VA Medical Center
RECRUITING

Louisville, Kentucky, 40206, United States

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Maine VA Health Care System
RECRUITING

Togus, Maine, 04330, United States

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Marshfield Clinic
RECRUITING

Marshfield, Wisconsin, 54449, United States

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Mayo Clinic
RECRUITING

Rochester, Minnesota, 55905, United States

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Mayo Clinic Health System SW Wisconsin
RECRUITING

La Crosse, Wisconsin, 54601, United States

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Mayo Clinic Health Systems - NW Wisconsin
RECRUITING

Eau Claire, Wisconsin, 54703, United States

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Medical College of Wisconsin
RECRUITING

Milwaukee, Wisconsin, 53295, United States

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Medical University of South Carolina
RECRUITING

Charleston, South Carolina, 29403, United States

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Meharry Medical College
RECRUITING

Nashville, Tennessee, 37208, United States

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Miami VA Medical Center
RECRUITING

Miami, Florida, 33125, United States

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Milwaukee VA Medical Center
RECRUITING

Milwaukee, Wisconsin, 53295, United States

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Minneapolis VA Health Care System
WITHDRAWN

Minneapolis, Minnesota, 55417, United States
Nashville VA Medical Center
RECRUITING

Nashville, Tennessee, 37212, United States

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North Chicago VA Medical Center
RECRUITING

North Chicago, Illinois, 60064, United States

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Northwell Health
RECRUITING

Manhasset, New York, 11030, United States

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Northwestern University
RECRUITING

Chicago, Illinois, 60208, United States

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Ochsner Clinic Foundation
RECRUITING

New Orleans, Louisiana, 70121, United States

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Ohio State University
RECRUITING

Columbus, Ohio, 43210, United States

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Omaha VA Medical Center
RECRUITING

Omaha, Nebraska, 68105, United States

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Oregon Health and Science University
NOT_YET_RECRUITING

Portland, Oregon, 97239, United States

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PREVENTABLE Tele-Site
RECRUITING

Durham, North Carolina, 27701, United States

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Providence VA Medical Center
RECRUITING

Providence, Rhode Island, 002908, United States

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Reno VA/Sierra Nevada Health Care
WITHDRAWN

Reno, Nevada, 89502, United States
Richmond VA
RECRUITING

Richmond, Virginia, 23219, United States

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Rush University Medical Center
RECRUITING

Chicago, Illinois, 60612, United States

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San Antonio VA Medical Center
RECRUITING

San Antonio, Texas, 78229, United States

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Southern Arizona VA Health Care System - Tucson
RECRUITING

Tucson, Arizona, 85723, United States

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St. Louis VA Medical Center
RECRUITING

St Louis, Missouri, 63106, United States

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Thomas Jefferson University
NOT_YET_RECRUITING

Philadelphia, Pennsylvania, 19107, United States

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University Medical Center
COMPLETED

New Orleans, Louisiana, 70112, United States
University of Alabama at Birmingham
RECRUITING

Birmingham, Alabama, 35205, United States

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University of Arkansas for Medical Sciences
RECRUITING

Little Rock, Arkansas, 72204, United States

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University of Chicago
RECRUITING

Chicago, Illinois, 60637, United States

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University of Florida
RECRUITING

Gainesville, Florida, 32610, United States

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University of Florida
RECRUITING

Jacksonville, Florida, 32608, United States

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University of Illinois at Chicago
RECRUITING

Chicago, Illinois, 60608, United States

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University of Iowa Healthcare
RECRUITING

Iowa City, Iowa, 52242, United States

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University of Kansas Medical Center
RECRUITING

Kansas City, Kansas, 66160, United States

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University of Miami
RECRUITING

Miami, Florida, 33136, United States

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University of Michigan
RECRUITING

Ann Arbor, Michigan, 48109, United States

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University of Mississippi Medical Center
RECRUITING

Jackson, Mississippi, 39216, United States

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University of Missouri Health System
RECRUITING

Columbia, Missouri, 65212, United States

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University of Nebraska Medical Center
RECRUITING

Omaha, Nebraska, 67105, United States

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University of North Carolina
RECRUITING

Chapel Hill, North Carolina, 27599, United States

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University of Pittsburgh Medical Center
RECRUITING

Pittsburgh, Pennsylvania, 15213, United States

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University of Texas Health Science Center at San Antonio
RECRUITING

San Antonio, Texas, 78229, United States

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University of Texas Southwestern Medical Center Dallas
RECRUITING

Dallas, Texas, 75390, United States

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University of Texas at Houston
RECRUITING

Houston, Texas, 77204, United States

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University of Utah
ACTIVE_NOT_RECRUITING

Salt Lake City, Utah, 84132, United States
VA Ann Arbor Healthcare System
RECRUITING

Ann Arbor, Michigan, 48105, United States

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VA Boston Healthcare System
RECRUITING

Boston, Massachusetts, 002130, United States

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VA Carribbean Healthcare
RECRUITING

San Juan, 00921, Puerto Rico

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VA Connecticut Healthcare System
RECRUITING

West Haven, Connecticut, 006111, United States

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VA Eastern Kansas Healthcare System
NOT_YET_RECRUITING

Topeka, Kansas, 66622, United States

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VA Greater Los Angeles
RECRUITING

Los Angeles, California, 90073, United States

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VA Hudson Valley Healthcare System
WITHDRAWN

Montrose, New York, 10548, United States
VA Madison Healthcare System
RECRUITING

Madison, Wisconsin, 53705, United States

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VA Medical Center Jackson
RECRUITING

Jackson, Mississippi, 39216, United States

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VA Medical Center Memphis
RECRUITING

Memphis, Tennessee, 38104, United States

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VA New York Harbor Healthcare System
NOT_YET_RECRUITING

New York, New York, 10010, United States

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VA Palo Alto Healthcare System
WITHDRAWN

Palo Alto, California, 94550, United States
VA Salt Lake City Healthcare System
RECRUITING

Salt Lake City, Utah, 84148, United States

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VA San Diego Medical Center
RECRUITING

San Diego, California, 92161, United States

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Vanderbilt University Medical Center
RECRUITING

Nashville, Tennessee, 37212, United States

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Wake Forest Baptist Hospital-Cardiology
RECRUITING

Winston-Salem, North Carolina, 27157, United States

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Wake Forest Hospital - Geriatrics
RECRUITING

Winston-Salem, North Carolina, 27157, United States

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Washington University in St. Louis
RECRUITING

St Louis, Missouri, 63130, United States

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Weill Cornell Medical College
RECRUITING

New York, New York, 10021, United States

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Yale University
RECRUITING

New Haven, Connecticut, 06520, United States

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Conditions

Explore the condition pages connected to this study.

CARDIOVASCULAR DISEASES COGNITIVE IMPAIRMENT, MILD DEMENTIA