New study tests if personalized cholesterol targets beat standard statins for seniors with diabetes
NCT ID NCT07359105
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing whether a personalized approach to lowering 'bad' cholesterol (LDL-C) works better than standard moderate-dose statins for preventing first heart attacks, strokes, or related events in people aged 70 and older with type 2 diabetes. About 2,186 participants will be randomly assigned to either moderate statin therapy or a treatment plan aimed at reaching a specific LDL target (using ezetimibe if needed). The goal is to see which strategy better prevents major cardiovascular events over up to 3 years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
statins (atorvastatin or rosuvastatin) and ezetimibe
What this could lead to
If successful, this could show that tailoring cholesterol treatment to individual targets is better than standard statin therapy for preventing first heart attacks or strokes in older adults with diabetes.
What could go wrong
This is a registry-based trial, not a classic double-blind study, so results may be less definitive. The benefit of intensive LDL lowering in this age group is still unproven, and the trial may not show a clear advantage.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Korea University ANAM Hospital
RECRUITINGSeoul, South Korea
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Severance Hospital
NOT_YET_RECRUITINGSeoul, South Korea