Can a phone app train your brain to beat the blues?

NCT ID NCT06735885

First seen Nov 05, 2025

Summary

This study tests a smartphone app called Matter Neuroscience that uses neurofeedback from brain scans to help people with mild to moderate depression better understand positive emotions. Researchers will enroll 240 adults to see if the app is safe and effective at reducing depression symptoms. The goal is to lay the groundwork for a larger, more definitive trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Stanford University Brain Stimulation Lab

    RECRUITING

    Stanford, California, 94304, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Matter Neuroscience App (smartphone application)

What this could lead to

If it works, this could point toward a new, non-drug way to ease depression symptoms using brain training at home.

What could go wrong

This is an early feasibility trial, so it is small and designed mainly to test safety and basic effectiveness. The app may not work for everyone, and results may not apply to severe depression.

Conditions

The condition(s) this trial relates to.

Depression depressive disorder major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.