New vein procedure could help millions who feel faint when standing

NCT ID NCT07195903

Recruiting now Disease control Sponsor: St. Francis Hospital, New York Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a minimally invasive procedure to open narrowed veins above the heart in people with orthostatic hypotension or intolerance—conditions that cause dizziness, fainting, or fatigue when standing. 100 adults who haven't improved with standard treatments will receive angioplasty or stenting and be followed for 2 years. The goal is to see if fixing these vein blockages can improve blood pressure control and reduce symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Venous angioplasty and stenting (jugular vein stenting)
What this could lead to: If it works, this could offer a new treatment option for people with orthostatic intolerance or hypotension who don't get relief from standard medications.
What could go wrong: This is an early, single-arm study with no placebo group, so results may be less reliable. The procedure carries risks like bleeding, infection, stroke, or stent problems.

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Conditions

The condition(s) this trial relates to.

orthostatic hypotension Orthostatic Intolerance postural orthostatic tachycardia syndrome Shy-Drager Syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ORTHOSTATIC HYPOTENSION, DYSAUTONOMIC ORTHOSTATIC INTOLERANCE

Contacts and locations

Locations

St. Francis Hospital The Heart Center
RECRUITING

Roslyn, New York, 11576, United States

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