Could a simple handgrip prevent fainting? new study investigates

NCT ID NCT06939153

Recruiting now Knowledge-focused Sponsor: Tracy Baynard Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how the heart and blood vessels communicate when blood pressure drops, like when standing up quickly. Researchers will test young and older men and women using a vacuum chamber around the legs to safely mimic low blood pressure. They will also see if squeezing a handgrip helps protect against blood pressure drops. The goal is to better understand why some people, especially older women, feel dizzy or faint, and whether a simple exercise could help.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could point toward simple handgrip exercises as a way to prevent dizziness and fainting when standing up, especially in older adults.
What could go wrong: This is a small, early-stage observational study with only 64 participants. It does not test a treatment, so any practical advice would require much larger follow-up trials.

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Conditions

The condition(s) this trial relates to.

Orthostatic Intolerance postural orthostatic tachycardia syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ORTHOSTATIC INTOLERANCE

Contacts and locations

Locations

University of Massachusetts Boston
RECRUITING

Boston, Massachusetts, 02125, United States

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