New hope for tiny tummies: drug trial targets deadly infant gut disease

NCT ID NCT06315738

Recruiting now Disease control Sponsor: Noveome Biotherapeutics, formerly Stemnion Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new drug called ST266 in premature infants with necrotizing enterocolitis (NEC), a severe gut infection. The trial will include 36 babies and aims to see if the drug is safe and tolerable at two different doses. Researchers will also look for early signs that it helps the gut heal faster.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ST266 (a biologic drug made from cells)
What this could lead to: If it works, this could point toward a new treatment for necrotizing enterocolitis, a life-threatening gut condition in premature infants.
What could go wrong: This is an early phase 1-2 trial with only 36 infants, so it is primarily testing safety. The drug may not prove effective, and there could be unknown side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

necrotizing enterocolitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NECROTIZING ENTEROCOLITIS

Contacts and locations

Locations

Arkansas Children's Hospital
RECRUITING

Little Rock, Arkansas, 72202, United States
BayCare Health System-St. Joseph's Women's Hospital
RECRUITING

Tampa, Florida, 33607, United States
NorthShore University-Evanston Hospital
RECRUITING

Evanston, Illinois, 60201, United States
Oklahoma Children's Hospital
RECRUITING

Oklahoma City, Oklahoma, 73104, United States
Penn State Health Milton S Hershey Medical Center/Penn State University College of Medicine
RECRUITING

Hershey, Pennsylvania, 17033, United States
University of Arkansas for Medical Sciences
RECRUITING

Little Rock, Arkansas, 72205, United States
University of Pittsburgh Medical Center Magee Womens Hospital
RECRUITING

Pittsburgh, Pennsylvania, 15219, United States
Yale-New Haven Hospital
RECRUITING

New Haven, Connecticut, 06510, United States

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